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The Story of GLP-1. “The next really good idea”. Episode 4

Beskrivelse

Thousands of years ago, it was good to have ‘thriftiness’ genes that enabled the body to preserve energy (calories) during cold winters. We are still equipped with these genes, but now they are really working against us by trying to preserve a body weight ‘setpoint’ that is too high in today’s environment. This has caused obesity to spread epidemically throughout the world, driving cardio-metabolic disease (type 2 diabetes and cardio-vascular disease) to become the #1 killer globally. The race for an effective way to treat these diseases started in the 1990’s with some important results for the GLP-1 hormone when given to animals and humans.
Follow “The next really good idea”, the last episode of the Novo Nordisk Foundation’s 2022 Advent Calendar “The Story of GLP-1”.”