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Protein-Membrane Costructures: Structure, Function, and Targeting

27 Nov
2018

Protein-Membrane Costructures: Structure, Function, and Targeting

Research in the biology and biophysics of lipids has surged in the past decade. Huge technical advances in lipidomics have allowed unprecedented insight into the complexity of lipid regulation in biological systems and lipid dysregulation in various diseases. The understanding of the importance of lipid-protein interactions has benefitted from equally large technical advances in structural biology, which have enabled the demonstration that lipids and proteins interact in a mutually regulatory manner in the membrane. Thus, many membrane protein structures would more correctly be referred to as protein–lipid costructures. This constitutes an emerging paradigm shift and an emerging research field with an immense potential, both in fundamental biology and in the context of cancer, diabetes and obesity, which are characterized by major changes in lipid metabolism.

The aim of this symposium is to bring together the most outstanding researchers working in the fields of lipid biophysics and lipid biology, structural biology and lipidomics in health and disease. The goal is to stimulate knowledge exchange between these fields and to educate young researchers in these fields about state-of-the-art techniques and conceptual advances.

The symposium will be followed up by a separate workshop on the day after the symposium, to further stimulate discussion, promote new collaborations and enable young researchers in Denmark to interact with the invited speakers.

Speakers

  • Ole G. Mouritsen, Department of Food Science, Faculty of Science, University of Copenhagen, Denmark
  • Almut Schulze, Theodor Boveri Institute, University of Würzburg Biocenter, Germany
  • Gunnar von Heijne, Department of Biochemistry and Biophysics, Stockholm University, Sweden
  • Gerhard Wagner, Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA, USA
  • Sarah Keller, Department of Chemistry, University of Washington, Seattle, WA, USA
  • Poul Nissen, Department of Molecular Biology and Genetics and DANDRITE Brain Research Center, Aarhus University, Denmark
  • Guillermo Montoya, Novo Nordisk Foundation Center for Protein Research, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark
  • Greg Fairn, St. Michaels Hospital, University of Toronto, Ontario, Canada
  • Ulrik Gether, Department of Neuroscience and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark
  • Peter Meikle, Baker Heart and Diabetes Institute, Melbourne, Australia
  • Daniel C. DiMaio, Department of Genetics, Yale School of Medicine, Boston, MA, USA

Chairs

  • Lise Arleth, Niels Bohr Institute, Faculty of Science, University of Copenhagen, Denmark
  • Bente Vestergaard, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark
  • Stine Falsig Pedersen, Department of Biology, Faculty of Science, University of Copenhagen, Denmark
  • Annette Eva Langkilde, Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, Denmark
  • Birthe B. Kragelund, Department of Biology, Faculty of Science, University of Copenhagen, Denmark

Who can attend

The symposium is open to participants of all career levels from student to professor.

Posters

All attendants are encouraged to bring a poster for the poster session within the following categories:

  • Membrane biophysics
  • Lipidomics
  • Roles of membrane lipids in regulating cell function
  • Lipid dysregulation in disease
  • Membrane protein structures
  • Novel tools for lipid visualization and manipulation

Posters will be exhibited during the symposium and discussed during a poster session.

If you wish to bring a poster, you must select participation with poster on the registration site.

Location: The Novo Nordisk Foundation, Tuborg Havnevej 19, 2900 Hellerup

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