Theme 1: Antibiotic resistance and/or alternative antibiotics
The theme is specifically focused on antibacterial research, and does not include research into resistance and resistance mechanisms of parasites, fungi and viruses. Examples within this theme include:
- Identification and testing of novel compounds with antibacterial effects, e.g., using screening of chemical libraries, natural products or through other means.
- Identification and characterisation of drug resistance and sensitivity mechanisms, e.g., through sequencing or molecular and structural characterisation of key molecules, signalling mechanisms or resistant bacterial strains.
- Improvement of the efficacy and safety of existing antibacterial compounds.
- Development and adaptation of new diagnostic tools that enable a more rapid identification of bacterial strains in a clinical setting.
Theme 2: Oral drug-delivery of biopharmaceuticals
Examples within this theme include:
- Formulation technologies.
- Protein engineering (e.g., engineering therapeutic proteins to withstand gut enzymes).
- Physiological transport mechanisms in the gastrointestinal system.
- Nanoscale drug delivery systems (e.g., using liposomes or nanoparticles to encapsulate and transport drug molecules).
- Targeted drug delivery (targeting specific tissues or organs).
Read about the grant recipients and the awarded projects in our overview of grant recipients.