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Events og symposier

CHALLENGE 2025 SYMPOSIUM ECTOPIC FAT & CMD

11. juni 2024

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On Tuesday, 11 June 2024, the Novo Nordisk Foundation will host a symposium with the aim of bringing together the research community for an exciting afternoon of knowledge sharing and networking, with the ambition to facilitate research partnerships and lay the seeds for realising creative solutions and new technologies within the 2025 Challenge Programme theme:

Ectopic fat & CMD

At the symposium there will be exciting speakers invited as well as short talks on different topics and participants can enjoy nice food and networking.

Programme
12:30 – 13:00 Coffee and registration
13:00 – 13:10 Welcome by Arne Astrup, Senior Vice President, Novo Nordisk Foundation
13:10 – 13:40 Keynote Speaker: Professor Antonio Vidal-Puig, University of Cambridge
Title of presentation: Adipose tissue expandability, lipotoxicity and the metabolic syndrome
13:40 – 14:10 Keynote Speaker: Professor Hannele Yki-Järvinen, University of Helsinki
Title of presentation: Acquired and genetic causes of ectopic fat accumulation in the liver – lessons from human studies
14:10 – 14:30 Coffee Break
14:30 – 16:00 Short talks from submitted abstracts
Resolving Cell-Type-Specific Metabolic Landscapes by Spatial Mass Spectrometry
Nils Færgeman, University of Southern Denmark
Extracellular vesicles Biomarkers in Ectopic Fat Accumulation– Liquid Biopsies for Early Detection and Real-Time Monitoring of Metabolic Disorders
Carlos Salomon, The University of Queensland
Exploring ectopic fat dynamics and related tissue-specific circulating extracellular vesicles by comprehensive omic-analysis
Aase Handberg, Aalborg University Hospital
Circulating microRNAs associated with metabolic disease
Louise Dalgaard, Roskilde University, Denmark
The mismatch between low birthweight and carbohydrate overfeeding in the development of type 2 diabetes
Allan Vaag, Lund University
A role of the incretin GIP in regulating adipose tissue homeostasis?
Mette Rosenkilde, University of Copenhagen
16:00 – 16:25 Coffee Break
16:25 – 17:55 Short talks from submitted abstracts
Dissecting the role of liver fat as a marker or cause of metabolic dysfunction in humans
Faidon Magkos, University of Copenhagen
Exploring Ectopic Fat and Cardiometabolic Diseases Throughout Life
Signe Torekov, University of Copenhagen
Decoding weight gain defense mechanisms: A critical foundation for treatment of cardiometabolic disease
Christoffer Clemmensen, University of Copenhagen
Genetic loci that uncouple adiposity from its cardiometabolic comorbidities provide evidence for diverse underlying mechanisms
Nathalie Chami, The Novo Nordisk Foundation Center for Genomic Mechanisms of Disease, Broad Institute of Harvard and MIT
Linking cardiovascular and metabolic disorders – the role of white adipose tissue
Mikael Ryden, Karolinska Institute
Isolated perfused visceral fat preparations from rats and mice
Jens Holst, University of Copenhagen
17:55 – 18:00 Closing remarks by Mads Fiil Hjorth, Senior Scientific Lead, Novo Nordisk Foundation
18:00 – 20:00 Cocktail dinner

Workshop venue:
Novo Nordisk Foundation – Tuborg Havnevej 19 – 2900 Hellerup

2025 Challenge: Ectopic fat & CMD
The challenge is to understand causal factors in the development and consequences of ectopic fat accumulation, identifying novel targets and precision medicine strategies in disease prevention and treatment with a human-centric point of departure. The programme should through basic and applied research have a special focus on disruptive and innovative approaches to tackle the challenge and should include novel state-of-the-art technologies such as large-scale omics and imaging techniques (e.g., CT and MRI) allowing for non-invasive quantification.

We encourage applicants to focus on data representing diversity both in relation to gender, ethnicity, and associated conditions. The programme does not focus on the prevention or treatment of obesity per se, but the understanding of how ectopic fat cause adverse health effects and how this disease risk can best be reduced (with/without weight loss). Hence, the effects of weight loss, diets and physical activity could be studied for mechanistic understanding of disease modification.

Supported research may include but is not limited to:

  • Identifying and understanding underlying genetic and acquired mechanisms that cause ectopic fat accumulation in various tissues.
  • Understanding how ectopic fat causes adverse health effects (local and humoral mediators).
  • Understanding the beneficial effects of weight loss, physical activity and specific diets on ectopic fat accumulation and disease (e.g., T2DM & CVD) modification.
  • Research aimed at subgrouping based on measures of ectopic fat for precision risk assessment and treatment strategies.

For mere information

Maria Pico Kjeldsen
Student Assistant
[email protected]
  • Tilmeldingsfrist
    31. maj 2024
  • Hvem kan deltage
    Åben
  • Lokation
    Novo Nordisk Foundation - Tuborg Havnevej 19 - 2900 Hellerup